New publication in Analytical Chemistry
Our new paper, “Heptafluorobutyl Chloroformate Derivatization Enables Molecular-Ion-Centric Metabolite Screening and Fluorine-Assisted Elemental-Composition Assignment by GC–APCI–HRMS,” has been published in Analytical Chemistry. In this study, we introduce a rapid metabolite-screening workflow combining one-minute heptafluorobutyl chloroformate (HFBCF) derivatization with GC–APCI–HRMS. The approach generates abundant protonated molecular ions together with characteristic fluorine-containing mass signatures, facilitating molecular-formula assignment and identification of … Read more