Our research is primarily aimed at uncovering biochemical mechanisms underlying organismal responses to environmental and physiological challenges. We are a research group focused on developing and applying advanced bioanalytical methods to study metabolism across a broad range of organisms – from insects and cyanobacteria to plants and humans –  with particular emphasis on polar metabolites, hormones, bioactive peptides, and volatile organic compounds.

We operate a broad range of analytical platforms for targeted and untargeted metabolomics, lipidomics, fluxomics, and related analyses, based on LC-MS and GC-MS technologies. These platforms support both our in-house research and collaborative projects within the interdisciplinary environment of the Biology Centre. LABM contributes to high-impact publications and translates its expertise into applied outputs. These include analytical kits, protocols, and workflows for broader scientific use. A flagship example is the MetAmino® kit for amino acid analysis, developed by LABM and marketed in collaboration with Chromservis (Prague, Czech Republic).

The group is led by Martin Moos and currently consists of 15 researchers and technical staff. We actively collaborate with national and international partners on research projects that benefit from our bioanalytical expertise and methodological innovation.

Latest publications

Kiss É., et al. (2025) Cyanophycinase is required for heterotrophy in cyanobacteria. Journal of Biological Chemistry 301 : 110791.

Delawská K., et al. (2025) Discovery of nostatin A, an azole-containing proteusin with prominent cytostatic and pro-apoptotic activity. Organic & Biomolecular Chemistry 23 : 449-460.

Noriega F., et al. (2025) Approaches to quantify and manipulate insect hormone signals. Current Opinion in Insect Science 72 : 101425.

Moos M., et al. (2025) Metabolomic signatures associated with cold adaptation and seasonal acclimation of Drosophila: profiling of 43 species. Journal of Experimental Biology 228 : jeb250076.