The BCLAB mission is to study novel bioanalytical approaches and apply them into metabolite research of insects and other important living organims. Unique analytical platforms developed by the BCLAB team cover the analysis of a comprehensive set of metabolites, from small molecules derived from organic and amino acids, amines, over nucleosides, nucleotides, lipids, steroids, sugars or their conjugates to peptide sequencing. In addition to the own bioanalytical projects, the research group participates in interdisciplinary research of the Biology Centre where numerous research teams and associates profit from the developed analytical methodologies and the unique know-how of the bioanalytical group.
The cryoprotectants of C. costata were localized in larval tissues using MALDI-MS imaging and their metabolism, thermal behaviour, and protective functions were studied.
Thanks to a long collaboration with Professor Gerd Gäde this interesting article was published. You can find the whole article at this LINK
This article presents new GC-MS method for enantiomeric resolution of eight biologically important secondary amino acids.
Our colleague Martin Moos (Our team) as a co-author published the new article about winter survival of Culex pipiens and its energy reserves.
You can read something about this interensting topics this: https://www.sciencedirect.com/science/article/pii/S1095643321000180)
Petr Simek and Martin Moos attended the conference 20th School of Mass Spectrometry 2020, skolams2020.spektroskopie.cz. Petr Simek presented the usefulness of derivatizations in mass spectrometry and new trends in this field. Martin Moos told about isotopic labeling in metabolic pathway research....
Automated sample preparation platform for on-line GC-MS metabolomics
We present a new application of MetaboAuto® platform combining automatization and ethyl chloroformate derivatization. It is validated automation analytical technology for determination 90 metabolites and xenobiotics in human serum/plasma, urine and liver tissue. The application was developed and validated in our laboratory in cooperation with Pragolab
Download application note here: