We are pleased to announce a new Polish–Czech collaborative research grant focused on understanding how dietary fatty acids modulate immune responses to fungal infections. The project uses the wax moth Galleria mellonella as a well-established alternative infection model with strong relevance to mammalian innate immunity.
The main goal of the project is to determine whether fatty acid supplementation can enhance host resistance to the opportunistic fungal pathogen Conidiobolus coronatus. By combining infection biology with advanced transcriptomic, proteomic, metabolomic, and lipidomic analyses, the project aims to uncover molecular and metabolic mechanisms underlying nutrition-driven immune modulation.
Our laboratory contributes state-of-the-art LC-MS and GC-MS–based metabolomics and lipidomics, enabling detailed characterization of immune-related metabolic adaptations. The results are expected to provide new insights into non-pharmacological strategies for strengthening immunity, with potential relevance for human health, veterinary medicine, and sustainable disease management.
