The BCLAB mission is to study novel bioanalytical approaches and apply them into metabolite research of insects and other important living organims. Unique analytical platforms developed by the BCLAB team cover the analysis of a comprehensive set of metabolites, from small molecules derived from organic and amino acids, amines, over nucleosides, nucleotides, lipids, steroids, sugars or their conjugates to peptide sequencing. In addition to the own bioanalytical projects, the research group participates in interdisciplinary research of the Biology Centre where numerous research teams and associates profit from the developed analytical methodologies and the unique know-how of the bioanalytical group.
Automated sample preparation platform for on-line GC-MS metabolomics
We present a new application of MetaboAuto® platform combining automatization and ethyl chloroformate derivatization. It is validated automation analytical technology for determination 90 metabolites and xenobiotics in human serum/plasma, urine and liver tissue. The application was developed and validated in our laboratory in cooperation with Pragolab
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